Description

4-Chloro-2-Fluorobenzyl Chloride is a versatile and high-purity halogenated benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive chloromethyl group and specific halogen substitution pattern, enabling precise molecular construction for high-value intermediates. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality raw materials for complex synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzyl moiety.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the chloro and fluoro substitutions enhance biological activity.
• Liquid Crystal & OLED Material Production: Serves as a building block for advanced electronic materials and functional dyes.
• Cross-Coupling Reactions: Valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Polymer Chemistry: Monomer or modifier for the synthesis of specialty polymers with tailored properties.
• Chemical Research & Development: Essential reagent for exploring new synthetic pathways and developing novel compounds in academic and industrial labs.

Basic Information

Product Name	4-Chloro-2-Fluorobenzyl Chloride
CAS No.	87417-71-8
Molecular Formula	C7H5Cl2F
Molecular Weight	179.02 g/mol
Synonyms	1-(Chloromethyl)-4-chloro-2-fluorobenzene; 2-Fluoro-4-chlorobenzyl chloride; (4-Chloro-2-fluorophenyl)methyl chloride; alpha,4-Dichloro-2-fluoro-α-toluene; 4-Chloro-2-fluoro-1-(chloromethyl)benzene; 2-Fluoro-4-chloro-α-chlorotoluene; Benzene, 1-(chloromethyl)-4-chloro-2-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluorobenzyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.