Description

1,3-Dimethyl-1,5-Dihydro-4H-Pyrazolo-[3,4-D]Pyrimidin-4-One is a high-purity heterocyclic organic compound that serves as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in its role as a versatile building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries seeking reliable, high-quality intermediates for drug discovery and production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting kinase inhibition and other enzymatic pathways.
• Drug Discovery & Development: Used in medicinal chemistry for the research and development of new chemical entities (NCEs) and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of final active pharmaceutical ingredients, requiring high purity and consistency.
• Biochemical Research: Serves as a reference standard or a precursor in biochemical assays and pharmacological studies.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects and scale-up activities.
• Academic Research: Utilized in university and institutional laboratories for organic synthesis methodology development and heterocyclic chemistry studies.

Basic Information

Product Name	1,3-Dimethyl-1,5-Dihydro-4H-Pyrazolo-[3,4-D]Pyrimidin-4-One
CAS No.	87412-86-0
Molecular Formula	C7H8N4O
Molecular Weight	164.16 g/mol
Synonyms	1,3-Dimethyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one; 1,3-Dimethyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 1,3-Dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one; 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,3-dimethyl-1,5-dihydro-; 1,3-Dimethyl-4,5-dihydropyrazolo[3,4-d]pyrimidin-4-one; 1,3-Dimethylpyrazolo[3,4-d]pyrimidin-4(5H)-one
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-1,5-Dihydro-4H-Pyrazolo-[3,4-D]Pyrimidin-4-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and impurity profiles. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients and advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.