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[1R,5S,(+)]-Tropane-2α-Yl=10,11-Dihydro-5H-Dibenzo[A,D]Cycloheptene-5-Carboxylate CAS NO 87395-56-0


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CAS No.:87395-56-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[1R,5S,(+)]-Tropane-2α-Yl=10,11-Dihydro-5H-Dibenzo[A,D]Cycloheptene-5-Carboxylate is a high-purity, optically active tropane alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral intermediate or reference standard for the synthesis and study of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, receptor ligands, and other specialized therapeutics. Our product is supplied with a guaranteed Certificate of Analysis to ensure reliability for your most demanding applications.

Application

  • Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel tropane-based pharmaceuticals and investigational drugs.
  • Neurological Research: Used as a reference standard or precursor in studies targeting neurotransmitter systems, particularly for dopamine and serotonin receptor research.
  • Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents with optimized efficacy and selectivity.
  • Analytical Standard: Employed as a high-purity standard in analytical methods such as HPLC, LC-MS, and NMR for quality control and compound identification.
  • Biochemical Tool Compound: Utilized in in vitro assays to study binding affinity, enzyme inhibition, and other pharmacological mechanisms.
  • Academic & Institutional Research: Supports fundamental chemical and pharmacological research in university and government laboratories.

Basic Information

Item Details
Product Name [1R,5S,(+)]-Tropane-2α-Yl=10,11-Dihydro-5H-Dibenzo[A,D]Cycloheptene-5-Carboxylate
CAS No. 87395-56-0
Molecular Formula C24H25NO2
Molecular Weight 359.46 g/mol
Synonyms (+)-Tropanyl 10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5-carboxylate; (1R,5S)-(+)-Tropan-2α-yl 10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5-carboxylate; Dihydrodibenzocycloheptenyl tropane carboxylate; Tropane-dibenzocycloheptene conjugate; 87395-56-0; (1R,5S)-(+)-Tropan-2α-yl 10,11-dihydro-5H-dibenzo[a,d][7]annulene-5-carboxylate
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Quality Control

Every batch of [1R,5S,(+)]-Tropane-2α-Yl=10,11-Dihydro-5H-Dibenzo[A,D]Cycloheptene-5-Carboxylate is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with each shipment to ensure full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Optical Purity (Chiral HPLC) ≥ 99.0% ee
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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