Description

2-Pyrimidinecarboxylic Acid, Hydrazide (9Ci) is a versatile heterocyclic building block and key hydrazide derivative used in advanced organic synthesis. This compound matters as a crucial precursor for the development of pharmaceuticals, agrochemicals, and functional materials, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with pyrimidine cores, such as kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic structure for biological activity.
• Chemical Synthesis Building Block: The reactive hydrazide group facilitates the creation of hydrazones, azoles, and other nitrogen-containing heterocycles for material science and catalysis.
• Ligand and Chelator Precursor: Employed in the design and synthesis of specialized ligands for metal coordination chemistry and catalysis.
• Bioconjugation and Linker Chemistry: Useful in bioconjugation strategies for attaching molecules to proteins, surfaces, or other biomolecules.
• Academic and Industrial R&D: A valuable reagent for methodological development and exploratory chemistry in both academic and corporate research laboratories.

Basic Information

Product Name	2-Pyrimidinecarboxylic Acid, Hydrazide (9Ci)
CAS No.	87362-28-5
Molecular Formula	C5H6N4O
Molecular Weight	138.13 g/mol
Synonyms	Pyrimidine-2-carbohydrazide; 2-Pyrimidinecarbohydrazide; 2-Carbamoylpyrimidine hydrazide; 2-Hydrazinocarbonylpyrimidine; Pyrimidine-2-carboxylic acid hydrazide; 2-Pyrimidinecarboxylic acid hydrazide; 2-Pyridinecarboxylic acid, hydrazide (9CI) (related index name); Hydrazide of 2-pyrimidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinecarboxylic Acid, Hydrazide (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); it is recommended to handle and store under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.