Description

Pyrimidine, 2-(Chloromethyl)-4-Methoxy- (9Ci) is a versatile and reactive heterocyclic building block, specifically a chloromethyl-substituted pyrimidine derivative. This compound is of significant value in advanced organic synthesis, where it serves as a key intermediate for constructing more complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing pyrimidine cores, such as kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the pyrimidine moiety is a key structural feature.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials due to its reactive chloromethyl group.
• Custom Synthesis Building Block: Employed by fine chemical manufacturers for the contract synthesis of complex, customer-specific molecules on laboratory to pilot scale.

Basic Information

Item	Detail
Product Name	Pyrimidine, 2-(Chloromethyl)-4-Methoxy- (9Ci)
CAS No.	87273-20-9
Molecular Formula	C6H7ClN2O
Molecular Weight	158.58 g/mol
Synonyms	2-(Chloromethyl)-4-methoxypyrimidine; 4-Methoxy-2-(chloromethyl)pyrimidine; 2-Chloromethyl-4-methoxypyrimidine; 4-Methoxy-2-pyrimidinylmethyl chloride
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-(Chloromethyl)-4-Methoxy- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.