Description

β-Endorphin (6-21) is a specific, biologically active fragment of the endogenous opioid peptide β-endorphin. This synthetic peptide is crucial for research into pain modulation, stress response, and neuroendocrine regulation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience and analgesic drug discovery.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies investigating opioid receptor binding, signaling pathways, and the physiological effects of endorphins.
• Analgesic Mechanism Studies: Employed in preclinical research to understand pain perception and to screen for novel analgesic compounds that target the opioid system.
• Biochemical Assay Development: Serves as a critical component in developing and validating immunoassays (ELISA, RIA) and receptor-binding assays for β-endorphin and related peptides.
• Neuroendocrine Research: Applied in studies exploring the interaction between the nervous and endocrine systems, particularly in stress and immune function.
• Pharmaceutical Reference Standard: Used as a high-purity calibrant in quality control and analytical method development for peptide-based therapeutics.

Basic Information

Product Name	β-Endorphin (6-21)
CAS No.	87202-50-4
Molecular Formula	C81H123N21O22S
Molecular Weight	1747.06 g/mol
Synonyms	β-Endorphin (6-21); β-Endorphin fragment 6-21; Human β-Endorphin (6-21); Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr; β-Lipotropin (61-76); LPH (61-76); Endorphin, β- (6-21)
EINECS	Contact for details

Quality Control

Our β-Endorphin (6-21) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) providing batch-specific results is supplied with every order to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Solubility	Soluble in water, acetic acid, DMSO
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.