Description

4-(2-Succinimidyloxycarbonylethyl)Phenyl-10-Methylacridinium-9-Carboxylate is a highly reactive, N-hydroxysuccinimide (NHS) ester derivative of an acridinium compound, designed for efficient chemiluminescent labeling. This compound matters for its ability to form stable amide bonds with primary amines under mild conditions, making it an essential tool for sensitive detection and assay development. It is primarily needed by researchers and manufacturers in the diagnostics, life sciences, and pharmaceutical industries for applications such as immunoassay development, nucleic acid detection, and protein conjugation.

Application

• Chemiluminescent Immunoassay (CLIA) Development: As a key labeling reagent for antibodies and antigens in diagnostic test kits.
• Nucleic Acid Labeling and Detection: For conjugating to oligonucleotide probes used in hybridization assays and molecular diagnostics.
• Protein and Peptide Conjugation: Enabling the covalent attachment of chemiluminescent tags to biomolecules for detection and analysis.
• Biosensor Fabrication: Used to immobilize or label recognition elements on sensor surfaces to generate a light-based signal.
• Research & Development: A critical reagent in academic and industrial R&D for developing novel bioanalytical methods and assays.
• High-Throughput Screening (HTS): Employed in drug discovery platforms that utilize chemiluminescence as a readout mechanism.

Basic Information

Product Name	4-(2-Succinimidyloxycarbonylethyl)Phenyl-10-Methylacridinium-9-Carboxylate
CAS No.	87198-89-8
Molecular Formula	C28H23N3O6
Molecular Weight	497.50 g/mol
Synonyms	10-Methyl-9-(4-((2,5-dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)acridinium carboxylate; N-Succinimidyl 4-(10-methyl-9-acridinyl)benzoate; Acridinium NHS Ester; Acridinium-9-carboxylate, 10-methyl-, 4-(2-((2,5-dioxo-1-pyrrolidinyl)oxy)-2-oxoethyl)phenyl ester; Chemiluminescent Labeling Reagent; CLIA Labeling Agent; Acridinium ester NHS; AEE Label
EINECS	Contact for details

Quality Control

Our 4-(2-Succinimidyloxycarbonylethyl)Phenyl-10-Methylacridinium-9-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive diagnostic and research applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.