Description

Desmethyl Acridinium Nhs Ester is a highly reactive, activated ester derivative of acridinium, designed for efficient labeling of biomolecules. This compound is crucial for researchers and developers requiring stable, chemiluminescent conjugates for sensitive detection assays. It is primarily used by professionals in the life sciences, diagnostics, and pharmaceutical development sectors for applications such as immunoassays and nucleic acid hybridization.

Application

• Chemiluminescent Immunoassays (CLIA): A key labeling reagent for antibodies and antigens to create highly sensitive diagnostic test kits.
• Nucleic Acid Labeling & Detection: Used to tag oligonucleotide probes for applications in blotting, in-situ hybridization, and microarray analysis.
• Protein Conjugation & Bioconjugation: Facilitates the covalent attachment of acridinium labels to proteins, peptides, and other amine-containing biomolecules.
• Research & Development of Diagnostic Assays: Serves as a critical component in the development and optimization of new clinical and research diagnostic platforms.
• Biosensor Development: Employed in the fabrication of chemiluminescence-based biosensors for rapid pathogen or biomarker detection.
• High-Throughput Screening (HTS): Used as a detection reagent in automated screening assays for drug discovery and biomarker validation.

Basic Information

Product Name	Desmethyl Acridinium Nhs Ester
CAS No.	87198-87-6
Molecular Formula	C24H21N3O6
Molecular Weight	447.44 g/mol
Synonyms	10-Methyl-9(10H)-acridiniumcarboxylic acid, 2,5-dioxo-1-pyrrolidinyl ester; 9-Acridiniumcarboxylic acid, 10-methyl-, 2,5-dioxo-1-pyrrolidinyl ester; N-Hydroxysuccinimide ester of Desmethyl Acridinium; Acridinium NHS Ester; N-Succinimidyl Acridinium-9-carboxylate; Chemiluminescent Labeling Reagent; CLIA Labeling Reagent
EINECS	Contact for details

Quality Control

Our Desmethyl Acridinium Nhs Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance characteristics is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Functional Activity (Labeling Efficiency)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.