Description

H-Leu-Pro-Oh Hcl is a high-purity, protected dipeptide building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular control in the development of complex peptides and peptidomimetics. It serves as an essential intermediate for pharmaceutical R&D, particularly in the synthesis of active pharmaceutical ingredients (APIs) and novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: Key building block for the solid-phase and solution-phase synthesis of therapeutic peptides.
• Protease Inhibitor Research: Used in the development of inhibitors targeting enzymes like dipeptidyl peptidase IV (DPP-4).
• Bioconjugation: Serves as a spacer or linker molecule in the creation of peptide-drug conjugates and labeled biomolecules.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize peptide-based drug candidates.
• Biochemical Research: Utilized as a substrate or standard in enzymatic assays and metabolic pathway studies.
• Cosmeceutical Development: Investigated for use in bioactive peptides aimed at skincare and anti-aging formulations.

Basic Information

Product Name	H-Leu-Pro-Oh Hcl
CAS No.	87178-63-0
Molecular Formula	C11H21N3O3 • HCl
Molecular Weight	279.76 g/mol (Free base: 243.30 g/mol)
Synonyms	H-Leu-Pro-OH hydrochloride; L-Leucyl-L-proline hydrochloride; Leu-Pro dipeptide HCl; N-(tert-Butoxycarbonyl)-L-leucyl-L-proline hydrochloride (Boc-Leu-Pro-OH • HCl); (S)-2-((S)-2-Amino-4-methylpentanamido)pyrrolidine-1-carboxylic acid hydrochloride; 87178-63-0; Leu-Pro HCl; H-L-Leu-L-Pro-OH • HCl
EINECS	Contact for details

Quality Control

Our H-Leu-Pro-Oh Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.