Description

L-Proline, 1-(2-Hydroxyethyl)- (9Ci) is a chemically modified derivative of the amino acid L-proline, featuring a hydroxylethyl substitution on the pyrrolidine ring. This structural modification imparts unique physicochemical properties, making it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, peptide mimetics, and catalyst development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and cardiovascular systems.
• Peptidomimetics & Drug Discovery: Used to construct constrained peptide analogs and scaffolds that enhance metabolic stability and bioavailability in therapeutic candidates.
• Asymmetric Catalysis: Acts as a precursor for ligands and organocatalysts utilized in enantioselective synthesis, crucial for producing optically pure compounds.
• Agrochemical Synthesis: Employed in the development of advanced herbicides and plant growth regulators that require specific stereochemistry.
• Biochemical Research: Utilized as a probe or substrate in enzymatic studies and metabolic pathway analysis due to its modified proline structure.
• Cosmetic & Personal Care Ingredients: Functions as a precursor for specialty surfactants and conditioning agents that benefit from amino acid-based chemistry.

Basic Information

Product Name	L-Proline, 1-(2-Hydroxyethyl)- (9Ci)
CAS No.	87026-07-1
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	1-(2-Hydroxyethyl)-L-proline; (S)-1-(2-Hydroxyethyl)pyrrolidine-2-carboxylic acid; L-1-(2-Hydroxyethyl)proline; Hydroxyethylproline; 2-Pyrrolidinecarboxylic acid, 1-(2-hydroxyethyl)-, (S)-; NSC 163063; 1-(2-Hydroxyethyl)proline
EINECS	Contact for details

Quality Control

Our L-Proline, 1-(2-Hydroxyethyl)- (9Ci) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	Contact for details
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.