Description

4-Chloro-2-Fluoro-5-Nitroaniline is a high-purity, multi-functional aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogen and nitro substitution pattern makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated and chlorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides, leveraging its halogenated nitroaniline structure.
• Dye and Pigment Manufacturing: Serves as a versatile intermediate for synthesizing complex azo dyes and high-performance pigments.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating novel aromatic amines.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Nitroaniline
CAS No.	86988-02-5
Molecular Formula	C6H4ClFN2O2
Molecular Weight	190.56 g/mol
Synonyms	5-Nitro-2-fluoro-4-chloroaniline; 2-Fluoro-4-chloro-5-nitroaniline; 4-Chloro-2-fluoro-5-nitrobenzenamine; Benzenamine, 4-chloro-2-fluoro-5-nitro-; 86988-02-5; 4-Chloro-2-fluoro-5-nitro-phenylamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-5-Nitroaniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.