Description

Peptide YY (13-36) (Porcine, Rat) is a bioactive fragment of the gut hormone Peptide YY (PYY), specifically the PYY3-36 form, which acts as a selective agonist for the Y2 receptor. This compound is of significant value for metabolic and appetite regulation research, as it is a key mediator of the ileal brake mechanism and postprandial satiety signals. It is primarily needed by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on endocrinology, obesity, diabetes, and gastrointestinal disorders.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating Y2 receptor signaling pathways and function.
• Metabolic Disease Studies: Critical for in vitro and in vivo research targeting obesity, type 2 diabetes, and metabolic syndrome.
• Appetite Regulation Assays: Employed in experiments to understand and modulate central and peripheral mechanisms controlling food intake and energy homeostasis.
• Gastrointestinal Physiology: Applied in research on gut hormone secretion, motility, and the ileal brake effect.
• Drug Discovery & Development: Serves as a lead compound or biological tool for screening and developing novel therapeutics for weight management.
• Biochemical Reagent: Utilized in receptor binding assays, cell-based functional assays, and signal transduction studies.

Basic Information

Product Name	Peptide YY (13-36) (Porcine, Rat)
CAS No.	86895-09-2
Molecular Formula	C136H205N41O48
Molecular Weight	3105.3 g/mol
Synonyms	PYY (13-36); PYY3-36; Peptide YY Fragment 13-36; Ileal Peptide; Pancreatic Peptide YY (13-36); Peptide Tyrosine Tyrosine (13-36); PYY (3-36), porcine; PYY (3-36), rat; Gut Hormone PYY Fragment
EINECS	Contact for details

Quality Control

Our Peptide YY (13-36) (Porcine, Rat) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and impurity profiles to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.