Description

7-Bromo-5-(2-Fluorophenyl)-1-Methyl-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One is a high-purity, advanced pharmaceutical intermediate belonging to the benzodiazepine class of compounds. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-derived active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Preclinical Development: Serves as a critical material for producing compounds for pharmacological and toxicological evaluation.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API manufacturing.
• Chemical Biology Probes: Employed in the development of specialized probes for studying neurological receptors and pathways.

Basic Information

Product Name	7-Bromo-5-(2-Fluorophenyl)-1-Methyl-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One
CAS No.	86890-79-1
Molecular Formula	C₁₆H₁₂BrFN₂O
Molecular Weight	347.18 g/mol
Synonyms	7-Bromo-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1-Methyl-7-bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 86890-79-1; 7-Bromo-1-methyl-5-(o-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-(2-Fluorophenyl)-7-bromo-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-5-(2-Fluorophenyl)-1-Methyl-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.