Description

Hexadecanesulfonyl Fluoride is a high-purity, long-chain sulfonyl fluoride derivative, a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile reagent for introducing the sulfonyl fluoride functional group, which is pivotal in click chemistry, materials science, and pharmaceutical research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries seeking reliable, high-quality intermediates for sulfonylation and SuFEx (Sulfur Fluoride Exchange) click reactions.

Application

• SuFEx Click Chemistry: A key reagent for Sulfur Fluoride Exchange reactions, enabling the rapid and reliable construction of sulfonate ester and sulfonamide linkages in drug discovery and polymer science.
• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of bioactive molecules, including protease inhibitors and other therapeutic agents containing sulfonamide moieties.
• Polymer & Materials Science: Used in the surface functionalization of polymers and the creation of novel materials with specific chemical and physical properties.
• Agrochemical Synthesis: Employed in the development of new herbicides, fungicides, and insecticides that utilize sulfonyl-based chemistry.
• Chemical Biology Probes: Utilized for labeling and studying biological systems due to its selective reactivity with nucleophiles like amines and thiols.
• Lubricant & Fuel Additive Precursor: Acts as an intermediate in the synthesis of specialty surfactants and performance additives.

Basic Information

Product Name	Hexadecanesulfonyl Fluoride
CAS No.	86855-26-7
Molecular Formula	C₁₆H₃₃FO₂S
Molecular Weight	308.50 g/mol
Synonyms	1-Hexadecanesulfonyl fluoride; Palmitylsulfonyl fluoride; Cetyl sulfonyl fluoride; n-Hexadecylsulfonyl fluoride; Sulfonyl fluoride, hexadecyl-; Hexadecyl sulfonyl fluoride
EINECS	Contact for details

Quality Control

Our Hexadecanesulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and incompatible with strong bases and fluorides; keep the container tightly sealed to exclude moisture and store separately from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.