Description

Lhrh, Acetyl-2-(2-Naphthyl)-Ala(1)-4-F-Phe(2)-Trp(3)-Arg(6)- CAS NO 86855-16-5 is a synthetic, modified peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH). This compound is engineered for enhanced stability and binding affinity, making it a critical research tool and a potential precursor for therapeutic development. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on endocrinology, oncology, and advanced peptide chemistry.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel LHRH-based therapeutics.
• Endocrinology Studies: Used in vitro and in vivo to study the modulation of the hypothalamic-pituitary-gonadal axis, receptor binding kinetics, and hormone release mechanisms.
• Oncology Research: Investigated for applications in hormone-dependent cancers (e.g., prostate cancer, breast cancer) due to its targeted action on gonadotropin secretion.
• Peptide Chemistry & Conjugation: Acts as a sophisticated building block for creating more complex peptide-drug conjugates or labeled probes for diagnostic imaging.
• Biochemical Assay Development: Employed as a high-purity calibrant or competitor in competitive binding assays (ELISA, RIA) and activity tests.
• Veterinary Medicine Development: Explored for applications in animal breeding control and the treatment of reproductive disorders in livestock and companion animals.

Basic Information

Item	Details
Product Name	Lhrh, Acetyl-2-(2-Naphthyl)-Ala(1)-4-F-Phe(2)-Trp(3)-Arg(6)- CAS NO 86855-16-5
CAS No.	86855-16-5
Molecular Formula	C64H81FN14O11
Molecular Weight	1217.4 g/mol
Synonyms	Acetyl-[D-2-Nal1,4-F-D-Phe2,D-Trp3,D-Arg6]-LHRH; [Ac-D-2-Nal1,4-F-D-Phe2,D-Trp3,D-Arg6]-GnRH; Modified LHRH Antagonist Analog; Luteinizing Hormone-Releasing Hormone (6-D-Arg) analog; GnRH Antagonist Peptide; Cetrorelix-related analog; Gonadorelin (6-D-Arg) derivative
EINECS	Contact for details

Quality Control

Our Lhrh analog is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing purity, peptide content, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.