Description

Carbobenzoxy-Glycyl(P)-Leucyl-Alanine CAS NO 86835-16-7 is a synthetic peptide derivative featuring a carbobenzoxy (Cbz) protecting group and a phosphorylated glycine residue. This specialized compound is a crucial building block and research tool in peptide chemistry and biochemistry. It is primarily utilized by pharmaceutical researchers, biochemists, and fine chemical manufacturers for developing enzyme inhibitors and studying signal transduction pathways.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of peptide-based drug candidates and enzyme inhibitors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for investigating kinases, phosphatases, and proteases.
• Proteomics: Acts as a tool compound for studying protein phosphorylation events and related cellular signaling mechanisms.
• Fine Chemical Synthesis: Employed as a protected, phosphorylated amino acid derivative for the solid-phase or solution-phase synthesis of complex peptides.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and chemical biology.

Basic Information

Product Name	Carbobenzoxy-Glycyl(P)-Leucyl-Alanine
CAS No.	86835-16-7
Molecular Formula	C21H30N3O8P
Molecular Weight	483.45 g/mol
Synonyms	Cbz-Gly(P)-Leu-Ala-OH; Z-Gly(P)-Leu-Ala-OH; N-Carbobenzoxy-O-phosphono-L-glycyl-L-leucyl-L-alanine; Benzyloxycarbonyl-glycyl(P)-leucyl-alanine; Cbz-Gly(PO3H2)-Leu-Ala; Z-Gly(PO3H2)-Leu-Ala; (Benzyloxycarbonyl)glycyl(P)-leucylalanine; Nα-Cbz-O-phosphono-glycyl-L-leucyl-L-alanine
EINECS	Contact for details

Quality Control

Our Carbobenzoxy-Glycyl(P)-Leucyl-Alanine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment to maintain stability due to its hygroscopic and moisture-sensitive nature. For long-term storage, keep under an inert atmosphere. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.