Description

2-[(6-Bromo-4-Oxo-Quinazolin-3-Yl)Methylamino]-n-[(2-Methylphenyl)Carb Amoyl]Acetamide is a high-purity, synthetic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical chemical intermediate or pharmacological reference standard for the synthesis of novel therapeutic agents. It is primarily required by R&D laboratories and fine chemical manufacturers focused on oncology, kinase inhibition, and other targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel quinazoline-based drug candidates.
• Kinase Inhibitor Research: Used as a core scaffold or precursor in the development of selective kinase inhibitors for cancer therapy.
• Biochemical Tool Compound: Serves as a reference standard or probe in enzymatic assays and biological pathway studies.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for clients.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	2-[(6-Bromo-4-Oxo-Quinazolin-3-Yl)Methylamino]-n-[(2-Methylphenyl)Carb Amoyl]Acetamide
CAS No.	86816-92-4
Molecular Formula	C19H18BrN5O3
Molecular Weight	444.28 g/mol
Synonyms	N-[(2-Methylphenyl)carbamoyl]-2-[[(6-bromo-4-oxo-3-quinazolinyl)methyl]amino]acetamide; 2-[[(6-Bromo-4-oxo-3-quinazolinyl)methyl]amino]-N-(2-methylphenyl)carbamoylacetamide; Acetamide, 2-[(6-bromo-4-oxo-3-quinazolinyl)methyl]amino]-N-[(2-methylphenyl)carbamoyl]-; BRD-K4477 (research code); Quinazoline acetamide derivative
EINECS	Contact for details

Quality Control

Every batch of our 2-[(6-Bromo-4-Oxo-Quinazolin-3-Yl)Methylamino]-n-[(2-Methylphenyl)Carb Amoyl]Acetamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is kept sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.