Description

Dermorphin, o-Sulfated CAS NO 86807-55-8 is a chemically modified, sulfated derivative of the potent natural opioid peptide dermorphin. This modification enhances its stability and alters its receptor binding profile, making it a critical tool for advanced pharmacological and neurological research. It is primarily utilized by pharmaceutical R&D laboratories, academic institutions, and biotechnology companies focused on pain management, neurobiology, and the development of novel peptide-based therapeutics.

Application

• Neuroscience Research: Used as a selective ligand to study opioid receptor subtypes (mu, delta, kappa) and their signaling pathways in the central nervous system.
• Analgesic Drug Development: Serves as a reference compound or a lead structure in the design of new, non-addictive pain relief medications.
• Biochemical Assays: Employed in competitive binding assays, receptor autoradiography, and functional cell-based tests to evaluate compound efficacy.
• Metabolic Stability Studies: Investigated for its pharmacokinetic properties, including its resistance to enzymatic degradation compared to the native peptide.
• Academic & Clinical Research: Supports fundamental studies on pain mechanisms, addiction, and the physiological roles of endogenous opioid systems.

Basic Information

Product Name	Dermorphin, o-Sulfated
CAS No.	86807-55-8
Molecular Formula	C40H58N10O16S
Molecular Weight	966.99 g/mol
Synonyms	O-Sulfated Dermorphin; [Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2] (Sulfated); Dermorphin Sulfate; H-Tyr-D-Ala-Phe-Gly-Tyr(SO3H)-Pro-Ser-NH2; Tyr-D-Ala-Phe-Gly-Tyr(H2SO4)-Pro-Ser-NH2; Opioid peptide sulfate; Dermorphin O-sulfate ester
EINECS	Contact for details

Quality Control

Our Dermorphin, o-Sulfated is produced under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, peptide content, and residual solvent levels is provided with every shipment to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.