Description

Dimethyl 2-(Pyrimidin-4-Yl)Malonate is a high-purity organic building block and pharmaceutical intermediate characterized by its malonate ester and pyrimidine functional groups. This compound is valued for its versatility in synthesizing complex heterocyclic structures, particularly in medicinal chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing pyrimidine cores for antiviral, anticancer, or kinase inhibitor applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators that leverage the biological activity of the pyrimidine moiety.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for constructing complex molecules in academic and industrial R&D settings.
• Material Science Precursor: Potential use in the development of organic electronic materials, ligands for metal-organic frameworks (MOFs), or specialty polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	Dimethyl 2-(Pyrimidin-4-Yl)Malonate
CAS No.	86761-91-3
Molecular Formula	C9H10N2O4
Molecular Weight	210.19 g/mol
Synonyms	Dimethyl (pyrimidin-4-yl)malonate; 2-(Pyrimidin-4-yl)malonic Acid Dimethyl Ester; Propanedioic acid, 2-(4-pyrimidinyl)-, dimethyl ester; 4-Pyrimidinylmalonic Acid Dimethyl Ester; Dimethyl 4-Pyrimidinylmalonate; NSC 405124; (Pyrimidin-4-yl)malonic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Dimethyl 2-(Pyrimidin-4-Yl)Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.