Description

n-Acetyl-γ-Endorphin is a chemically modified, acetylated derivative of the endogenous neuropeptide γ-endorphin. This modification enhances its metabolic stability and alters its receptor interaction profile, making it a valuable tool for advanced neuroscience and pharmaceutical research. It is primarily utilized by research institutions and pharmaceutical developers investigating the opioid system, neuropsychiatric disorders, and novel peptide-based therapeutics.

Application

• Neuroscience Research: Used as a reference standard and experimental ligand in studies of opioid receptor subtypes (e.g., mu, delta, epsilon) and their downstream signaling pathways.
• Psychopharmacology: Investigated for its potential role in modulating behaviors related to stress, reward, and mood, contributing to the development of new therapeutic targets.
• Biochemical Assay Development: Serves as a critical component in the development and validation of immunoassays (ELISA, RIA) and receptor binding assays.
• Peptide Drug Discovery: Acts as a lead compound or intermediate for the synthesis and structure-activity relationship (SAR) studies of novel analgesic or neuroprotective agents.
• Academic & Clinical Research: Employed in university and hospital laboratories for fundamental research into endorphin physiology and pathophysiology.

Basic Information

Product Name	n-Acetyl-γ-Endorphin
CAS No.	86741-97-1
Molecular Formula	C86H122N20O23
Molecular Weight	1771.03 g/mol
Synonyms	Acetyl-γ-Endorphin; N-Acetyl-γ-Endorphin; N-Acetyl-γ-Endorphin; Acetyl-γ-Endorphin; α-N-Acetyl-β-endorphin (1-17); β-Endorphin (1-17), N-acetyl-; Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu, N-acetyl-; L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-threonyl-L-seryl-L-glutamyl-L-lysyl-L-seryl-L-glutaminyl-L-threonyl-L-prolyl-L-leucyl-L-valyl-L-threonyl-L-leucine, N-acetyl-
EINECS	Contact for details

Quality Control

Our n-Acetyl-γ-Endorphin is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	≤ 10.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.