Description

1-Propanone, 2-Chloro-1-(3-Fluoro-4-Hydroxyphenyl)- (9Ci) is a specialized fluorinated aromatic ketone derivative, serving as a critical advanced intermediate in modern synthetic organic chemistry. Its unique molecular structure, featuring both chloro and fluoro substituents on a phenolic ketone backbone, makes it a valuable building block for constructing complex molecules with targeted biological or material properties. This high-purity compound is primarily utilized by research institutions and industrial R&D departments engaged in the development of novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances bioavailability and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in organic synthesis for introducing the 3-fluoro-4-hydroxyphenyl moiety into more complex molecular architectures via further functionalization reactions.
• Life Science Research: Utilized in biochemical and pharmacological research as a probe or standard for studying enzyme interactions and receptor binding.

Basic Information

Product Name	1-Propanone, 2-Chloro-1-(3-Fluoro-4-Hydroxyphenyl)- (9Ci)
CAS No.	86615-79-4
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	2-Chloro-1-(3-fluoro-4-hydroxyphenyl)propan-1-one; 2-Chloro-1-(3-fluoro-4-hydroxyphenyl)-1-propanone; 1-Propanone, 2-chloro-1-(3-fluoro-4-hydroxyphenyl)-; 3-Fluoro-4-hydroxy-2-chloropropiophenone; 2'-Chloro-3'-fluoro-4'-hydroxypropiophenone; α-Chloro-3-fluoro-4-hydroxypropiophenone; NSC 406915; CAS 86615-79-4
EINECS	Contact for details

Quality Control

Our production of 1-Propanone, 2-Chloro-1-(3-Fluoro-4-Hydroxyphenyl)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.