Description

Enkephalin-Met, Arg(6)-Gly(7)-Leu(8)-Lys(9)- CAS NO 86533-29-1 is a synthetic peptide analog of the endogenous opioid peptide [Met]-enkephalin, modified with a C-terminal extension. This modification is designed to enhance its stability and receptor interaction profile, making it a valuable tool for advanced neuroscience and pharmacological research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in the study of opioid receptor signaling, pain pathways, and neuropeptide function.

Application

• Neuroscience Research: As a key reagent for studying the binding affinity, selectivity, and functional activity of opioid receptors (e.g., δ, μ) in vitro and in vivo.
• Pharmacological Assay Development: Used as a reference standard or active compound in high-throughput screening (HTS) campaigns to discover novel analgesics or receptor modulators.
• Biochemical Studies: Investigation of peptide stability, metabolism, and structure-activity relationships (SAR) to design peptides with improved therapeutic profiles.
• Cell Signaling Research: Tool for probing intracellular pathways activated by opioid receptor engagement, such as cAMP inhibition or MAPK/ERK signaling.
• Academic & Institutional Research: Fundamental research into the role of enkephalins in pain modulation, reward systems, and neurological disorders.

Basic Information

Product Name	Enkephalin-Met, Arg(6)-Gly(7)-Leu(8)-Lys(9)- CAS NO 86533-29-1
CAS No.	86533-29-1
Molecular Formula	C34H56N12O9
Molecular Weight	752.89 g/mol
Synonyms	[Arg6, Gly7, Leu8, Lys9]-Met-Enkephalin; H-Tyr-Gly-Gly-Phe-Met-Arg-Gly-Leu-Lys-OH; Met-Enkephalin (6-9) extended peptide; Opioid receptor ligand peptide; YGGFMRGLK; MRGLK-extended [Met]-Enkephalin
EINECS	Contact for details

Quality Control

Our Enkephalin-Met, Arg(6)-Gly(7)-Leu(8)-Lys(9)- is produced under stringent conditions to ensure high purity and batch-to-batch consistency for research applications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC and MS, are validated to provide reliable data for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.