Description

Grf (1-43) (Rat) is a synthetic peptide fragment corresponding to the N-terminal 43 amino acid sequence of rat growth hormone-releasing factor (GRF). This high-purity peptide is a critical research tool for studying the structure, function, and signaling pathways of GRF in neuroendocrine and metabolic research. It is essential for scientists and R&D teams in the pharmaceutical, biotechnology, and academic sectors focused on endocrinology, peptide hormone analogs, and metabolic disorder research.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the mechanisms of growth hormone secretion and regulation.
• Drug Discovery & Development: Serves as a key starting material or intermediate in the synthesis and screening of novel GRF analogs and growth hormone secretagogues.
• In Vitro Assays: Employed in cell-based assays and receptor binding studies to evaluate biological activity and potency.
• Antibody Production: Acts as an immunogen for generating specific polyclonal or monoclonal antibodies against GRF for diagnostic and research applications.
• Metabolic Studies: Utilized in animal models to explore the role of GRF in growth, metabolism, and related disorders.
• Quality Control: Functions as a certified reference material (CRM) for the analytical validation and quality assurance of related pharmaceutical products.

Basic Information

Item	Detail
Product Name	Grf (1-43) (Rat)
CAS No.	86472-71-1
Molecular Formula	C215H358N72O66S
Molecular Weight	~4969.6 g/mol
Synonyms	Rat GRF (1-43); Rat Growth Hormone-Releasing Factor (1-43); Somatoliberin (1-43), rat; rGRF(1-43); Growth Hormone-Releasing Hormone (1-43), rat; hpGRF (1-43), rat; Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 (Sequence)
EINECS	Contact for details

Quality Control

Our Grf (1-43) (Rat) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing purity, peptide content, and solvent residues, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.