Description

7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid is a high-purity pharmaceutical intermediate of significant commercial and research importance. This compound serves as a critical building block in the synthesis of advanced fluoroquinolone antibiotics, valued for its precise molecular structure. It is essential for manufacturers and R&D laboratories in the pharmaceutical and fine chemical sectors requiring reliable, high-quality raw materials for API development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of next-generation fluoroquinolone antibacterial agents.
• Active Pharmaceutical Ingredient (API) Development: Used in research and scale-up processes for developing new antibiotic formulations.
• Chemical Synthesis: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Used in studies targeting bacterial DNA gyrase and topoisomerase IV enzymes.
• Custom Synthesis: A starting material for the preparation of novel quinoline derivatives with potential therapeutic activity.

Basic Information

Product Name	7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid
CAS No.	86393-33-1
Molecular Formula	C₁₃H₉ClFNO₃
Molecular Weight	281.67 g/mol
Synonyms	7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 3-Quinolinecarboxylic acid, 7-chloro-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-; 86393-33-1; Ciprofloxacin intermediate; Ciprofloxacin carboxylic acid derivative; 7-Chloro-6-fluoro-1-cyclopropyl-4-oxoquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.