Description

Cholecystokinin (27-32)-Amide is a bioactive peptide fragment derived from the C-terminal sequence of the cholecystokinin (CCK) hormone. This compound is of significant value in biochemical and pharmacological research due to its role in studying receptor binding, signal transduction, and digestive system functions. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focusing on neurogastroenterology and peptide-based therapeutics.

Application

• Biochemical Research: Used as a standard or probe in studies of CCK receptor subtypes (CCKA and CCKB) and their associated signaling pathways.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the discovery and development of drugs targeting gastrointestinal disorders, appetite regulation, and anxiety.
• Diagnostic Assays: Employed in the development of immunoassays (ELISA, RIA) for the detection and quantification of CCK-related peptides in biological samples.
• Neuroscience Studies: Applied in experimental models to investigate the role of CCK in the brain-gut axis, pain perception, and behavioral responses.
• Academic & Clinical Research: Utilized in university and hospital laboratories for fundamental research on peptide hormones and their fragments.

Basic Information

Product Name	Cholecystokinin (27-32)-Amide
CAS No.	86367-90-0
Molecular Formula	C38H55N9O9S
Molecular Weight	813.97 g/mol
Synonyms	CCK (27-32)-Amide; CCK-6 Amide; Cholecystokinin Hexapeptide Amide; Asp-Tyr(SO3H)-Met-Gly-Trp-Met-NH2; Sincalide fragment (27-32) amide; CCK-6; Sulfated CCK (27-32) Amide
EINECS	Contact for details

Quality Control

Our Cholecystokinin (27-32)-Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and impurity profiles are provided to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Amino Acid Composition	Within ±10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.