Description

9-(1,3-Diacetate-2-Propoxymethyl)Guanine is a key guanine derivative and a vital pharmaceutical intermediate. This compound matters for its role in the synthesis of nucleoside analogs, which are foundational to antiviral and anticancer therapeutic development. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in advanced drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies involving DNA/RNA synthesis, enzyme inhibition, and mechanism of action investigations.
• Process Chemistry: Serves as a precursor in the scaled-up manufacturing of active pharmaceutical ingredients (APIs).
• Antiviral Drug Development: A key intermediate for prodrug development targeting herpesviruses and other viral pathogens.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and novel compound library generation.

Basic Information

Product Name	9-(1,3-Diacetate-2-Propoxymethyl)Guanine
CAS No.	86357-19-9
Molecular Formula	C14H19N5O6
Molecular Weight	353.33 g/mol
Synonyms	9-[(2-Acetoxy-1-(acetoxymethyl)ethoxy)methyl]guanine; 9-(2-Acetoxy-1-acetoxymethylethoxymethyl)guanine; 2'-Acetoxy-1'-acetoxymethylethoxymethylguanine; 9-[(1,3-Diacetoxy-2-propoxy)methyl]guanine; Ganciclovir Diacetate Ester; Ganciclovir Di-O-acetate; GCV Diacetate; DAGV
EINECS	Contact for details

Quality Control

Our 9-(1,3-Diacetate-2-Propoxymethyl)Guanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant use and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.