Description

(Tyr34)-Pth (7-34) Amide (Bovine) is a synthetic peptide fragment derived from the bovine parathyroid hormone sequence, specifically the 7-34 region with a tyrosine substitution at position 34 and an amidated C-terminus. This modification enhances its stability and receptor-binding affinity, making it a critical tool for biochemical research and pharmaceutical development. It is primarily utilized by research institutions and biotechnology companies focused on calcium metabolism studies, bone disease research, and the development of novel PTH-related therapeutics.

Application

• Biochemical Research: Used as a reference standard and active ligand in studies of parathyroid hormone (PTH) receptor binding, signal transduction pathways, and structure-activity relationships (SAR).
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the R&D of novel therapeutics for osteoporosis, hyperparathyroidism, and other bone metabolic disorders.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays and bioassays designed to measure PTH activity or screen for receptor agonists/antagonists.
• Cell Biology Studies: Applied in cell culture experiments to investigate the effects of PTH analogs on osteoblast and osteoclast activity, calcium flux, and gene expression.
• Academic Research: A vital reagent for university and institutional labs exploring endocrinology, mineral homeostasis, and peptide hormone pharmacology.

Basic Information

Product Name	(Tyr34)-Pth (7-34) Amide (Bovine)
CAS No.	86292-93-5
Molecular Formula	C147H238N44O43S2
Molecular Weight	3348.9 g/mol
Synonyms	Bovine PTH (7-34) amide, [Tyr34]-PTH (7-34)-NH2; [Tyr34]-Parathyroid Hormone (7-34) amide; PTH (7-34) (Bovine) [Tyr34] amide; Parathyroid Hormone Fragment 7-34 (Bovine) [Tyr34] amide; [Tyr34]bPTH(7-34)NH2; bPTH(7-34)-Tyr34-NH2; PTH-related peptide analog
EINECS	Contact for details

Quality Control

Every batch of (Tyr34)-Pth (7-34) Amide (Bovine) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) providing detailed results for purity (HPLC), peptide content, amino acid analysis, and mass spectrometry (MS) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by Mass Spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Complies with theoretical composition
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.