Description

Copeptin (Rat) is a synthetic peptide fragment corresponding to the C-terminal portion of rat arginine vasopressin (AVP) prohormone. This biomarker is of significant value in preclinical research for studying stress response, cardiovascular function, and endocrine regulation. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on rodent models of disease.

Application

• Biomarker Research: Used as a stable surrogate marker for AVP release in rat models of sepsis, heart failure, and stroke.
• Preclinical Assay Development: Essential for the development and validation of immunoassays (e.g., ELISA) to measure copeptin levels in rodent plasma/serum.
• Endocrinology Studies: Facilitates research into the vasopressin system, osmoregulation, and stress hormone pathways in rats.
• Drug Efficacy Testing: Serves as a key pharmacodynamic endpoint in evaluating novel therapeutics for cardiovascular and renal diseases.
• Toxicology & Safety Assessment: Monitored in rodent studies to assess compound-induced stress or organ toxicity.
• Reference Standard: Acts as a high-purity calibrator or control material in quantitative bioanalytical methods.

Basic Information

Product Name	Copeptin (Rat)
CAS No.	86280-64-0
Molecular Formula	C81H123N23O26S
Molecular Weight	1827.0 g/mol (approximately)
Synonyms	Rat Copeptin; C-terminal provasopressin (rat); AVP precursor fragment 126-164 (rat); Glycopeptin (rat); Preprovasopressin C-terminal peptide (rat); CPP (rat); C-terminal pro-arginine-vasopressin (rat); CT-proAVP (rat)
EINECS	Contact for details

Quality Control

Our Copeptin (Rat) is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for critical research. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to relevant guidelines for research-grade peptides, ensuring suitability for immunoassay development and preclinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.