Description

[2-Fluoro-3-(Trifluoromethoxy)Phenyl]Methanol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of fluorine and trifluoromethoxy substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of novel drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where fluorine motifs enhance bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Advanced Polymer Chemistry: Incorporated into specialty polymers to impart unique chemical resistance and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce complex fluorinated aromatic systems.

Basic Information

Product Name	[2-Fluoro-3-(Trifluoromethoxy)Phenyl]Methanol
CAS No.	86256-43-1
Molecular Formula	C8H6F4O2
Molecular Weight	210.13 g/mol
Synonyms	(2-Fluoro-3-(trifluoromethoxy)phenyl)methanol; 1-(2-Fluoro-3-(trifluoromethoxy)phenyl)methanol; 2-Fluoro-3-(trifluoromethoxy)benzyl alcohol; α-Fluoro-α'-(trifluoromethoxy)benzyl alcohol; [2-Fluoro-3-(trifluoromethoxy)phenyl]carbinol; 86256-43-1; 2-Fluoro-3-trifluoromethoxybenzyl alcohol
EINECS	Contact for details

Quality Control

Every batch of [2-Fluoro-3-(Trifluoromethoxy)Phenyl]Methanol is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.