Description

6-(4-Methoxy-Phenyl)-4-Phenyl-5,6-Dihydro-1H-Pyrimidine-2-Thione is a high-purity, advanced pharmaceutical intermediate belonging to the dihydropyrimidine-thione class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and for research into novel therapeutic agents. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory conditions, and infectious diseases.
• Agrochemical Research: Serves as a core structure for developing new pesticides, herbicides, and fungicides due to its bioactive heterocyclic scaffold.
• Organic Synthesis Building Block: Utilized in academic and industrial research laboratories for constructing complex molecular architectures and exploring novel chemical reactions.
• Material Science: Investigated for potential applications in creating specialty polymers or organic electronic materials due to its conjugated system.

Basic Information

Product Name	6-(4-Methoxy-Phenyl)-4-Phenyl-5,6-Dihydro-1H-Pyrimidine-2-Thione
CAS No.	86212-45-5
Molecular Formula	C18H16N2OS
Molecular Weight	308.40 g/mol
Synonyms	4-Phenyl-6-(4-methoxyphenyl)-5,6-dihydro-2(1H)-pyrimidinethione; 6-(4-Methoxyphenyl)-4-phenyl-3,4-dihydropyrimidine-2(1H)-thione; 4-Phenyl-6-(p-methoxyphenyl)-5,6-dihydro-2-mercaptopyrimidine; 86212-45-5; Dihydro-2-mercaptopyrimidine derivative; 5,6-Dihydro-1H-pyrimidine-2-thione derivative
EINECS	Contact for details

Quality Control

Our 6-(4-Methoxy-Phenyl)-4-Phenyl-5,6-Dihydro-1H-Pyrimidine-2-Thione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.