Description

Dopexamine is a synthetic catecholamine and a potent agonist for dopamine and β-2 adrenergic receptors. This compound is of significant interest in pharmaceutical research and development, particularly for its cardiovascular effects. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents for conditions such as heart failure and septic shock. Dopexamine CAS NO 86197-47-9 represents a key intermediate and reference standard in these critical areas of medical science.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the development of cardiovascular drugs.
• Cardiovascular Pharmacology Studies: Used in preclinical and clinical research to investigate inotropic and vasodilatory effects for potential heart failure treatments.
• Septic Shock Research: Employed in studies exploring pharmacological interventions to improve renal and splanchnic blood flow in critical care medicine.
• Biochemical Assay Development: Acts as a standard compound in the development and validation of analytical methods (e.g., HPLC, LC-MS) for catecholamine detection.
• Receptor Binding Studies: Utilized in vitro to study agonist activity and binding affinity at dopamine (DA1) and β-2 adrenergic receptors.
• Academic Research: Provides a tool for university laboratories studying adrenergic and dopaminergic signaling pathways and their physiological roles.

Basic Information

Product Name	Dopexamine
CAS No.	86197-47-9
Molecular Formula	C₂₄H₃₂N₂O₄
Molecular Weight	412.53 g/mol
Synonyms	Dopexamine Hydrochloride; FPL 60278AR; 4-[2-[[6-[(2-Phenylethyl)amino]hexyl]amino]ethyl]benzene-1,2-diol; 1,2-Benzenediol, 4-[2-[[6-[(2-phenylethyl)amino]hexyl]amino]ethyl]-; FPL-60278; Dopacard (brand name); (R)-Dopexamine
EINECS	Contact for details

Quality Control

Our Dopexamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of specified impurities to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity: ≤0.5%; Total impurities: ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.