Description

3-Fluoro-4-Nitrobenzenesulfonyl Chloride is a high-purity, reactive aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the sulfonyl chloride group acts as a versatile electrophile for sulfonamide formation, and the electron-withdrawing nitro and fluoro substituents direct further chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs), intermediates for crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and pesticides with enhanced efficacy.
• Dyestuff and Pigment Production: Intermediate in the manufacture of specialty dyes and colorants.
• Polymer Chemistry: Used to introduce sulfonyl groups into polymers for modifying thermal and chemical resistance.
• Chemical Research & Development: A versatile reagent for constructing complex molecular architectures in medicinal and process chemistry.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in catalytic systems.

Basic Information

Product Name	3-Fluoro-4-Nitrobenzenesulfonyl Chloride
CAS No.	86156-93-6
Molecular Formula	C6H3ClFNO4S
Molecular Weight	239.61 g/mol
Synonyms	4-Nitro-3-fluorobenzenesulfonyl chloride; 3-Fluoro-4-nitrobenzene-1-sulfonyl chloride; 1-Fluoro-2-nitro-4-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 3-fluoro-4-nitro-; 3-Fluoro-4-nitrobenzenesulphonyl chloride; 3-Fluoro-4-nitro-phenylsulfonyl chloride; 4-Nitro-3-fluorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Nitrobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.