Description

N(Alpha)-Acetyl(Fluorophenylalanyl (106))Troponin I (104-115)Amide is a synthetic peptide fragment derived from the cardiac regulatory protein Troponin I, specifically modified with an acetyl group and a fluorinated phenylalanine residue. This compound is of significant value as a high-purity biochemical tool for advanced cardiovascular research and diagnostic assay development. It is primarily needed by pharmaceutical R&D teams, diagnostic manufacturers, and academic research institutions focusing on cardiac biomarker discovery, myocardial infarction studies, and the development of high-sensitivity immunoassays.

Application

• Cardiac Biomarker Research: Used as a critical reference standard and antigen in studies investigating Troponin I release and kinetics during cardiac events.
• Diagnostic Assay Development: Serves as a key calibrator, immunogen, or competitive binder in the development and validation of ELISA and chemiluminescence immunoassays (CLIA) for cardiac troponin detection.
• Antibody Production & Characterization: Employed to generate and screen monoclonal or polyclonal antibodies with high specificity for the modified epitope region of Troponin I.
• Proteomics & Signal Transduction Studies: Utilized in model systems to study post-translational modifications and their functional impact on cardiac muscle regulation.
• Quality Control in Diagnostics: Acts as a precision control material to ensure the accuracy and consistency of commercial cardiac diagnostic test kits.

Basic Information

Product Name	N(Alpha)-Acetyl(Fluorophenylalanyl (106))Troponin I (104-115)Amide
CAS No.	86129-34-2
Molecular Formula	C66H95FN16O19
Molecular Weight	1419.55 g/mol
Synonyms	Acetyl-Fluorophenylalanyl-Troponin I (104-115) Amide; cTnI (104-115) Amide, Acetylated, Fluorinated; N-α-Acetyl-L-4-fluorophenylalanyl-troponin I (104-115) amide; Cardiac Troponin I Fragment (104-115), Modified; Fluorinated cTnI Peptide; Ac-F(106)cTnI(104-115)-NH2; Diagnostic Peptide Standard 86129-34-2
EINECS	Contact for details

Quality Control

This high-purity peptide is manufactured under controlled conditions and undergoes rigorous analytical characterization. Every batch is tested to ensure identity, purity, and consistency, with a typical HPLC purity ≥95%. Comprehensive Certificates of Analysis (COA) detailing mass spectrometry (MS), HPLC chromatograms, and amino acid analysis (AAA) are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Amino Acid Composition	Within ±10% of theoretical
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid, or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.