Description

Pyr-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-Nh2 is a synthetic decapeptide amide, also known as Gonadorelin, which acts as a potent agonist of the gonadotropin-releasing hormone (GnRH) receptor. This compound is crucial for research and development in endocrinology and reproductive medicine, serving as a key reference standard and active pharmaceutical ingredient. It is primarily needed by pharmaceutical manufacturers, biotechnology research institutions, and clinical diagnostic developers focusing on hormone-related therapies and diagnostic assays.

Application

• Pharmaceutical Active Ingredient (API): Used in the formulation of therapeutic drugs targeting hormonal disorders and fertility treatments.
• Biomedical Research Standard: Serves as a critical reference standard in laboratory studies of the hypothalamic-pituitary-gonadal axis and GnRH receptor function.
• Diagnostic Reagent Manufacturing: Employed in the production of in-vitro diagnostic (IVD) kits and immunoassays for measuring hormonal levels.
• Veterinary Medicine: Applied in veterinary pharmaceuticals for reproductive management in livestock and companion animals.
• Peptide Chemistry & Process Development: Utilized as a model compound in the development and optimization of peptide synthesis, purification, and analytical methods.
• Academic & Institutional Research: Supports fundamental research in universities and institutes studying neuroendocrinology and peptide signaling pathways.

Basic Information

Product Name	Pyr-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-Nh2
CAS No.	86073-88-3
Molecular Formula	C55H75N17O13
Molecular Weight	1182.31 g/mol
Synonyms	Gonadorelin; GnRH; LHRH; Luliberin; Gonadotropin-Releasing Hormone; Factrel; Cystorelin; Pyroglutamyl-histidyl-tryptophyl-seryl-tyrosyl-glycyl-tryptophyl-leucyl-prolyl-glycinamide; Gonadoliberin; LH/FSH-RH
EINECS	Contact for details

Quality Control

Our Pyr-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances to ensure compliance with high-grade pharmaceutical standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature of 15-25°C or as specified on the label. Due to its hygroscopic nature, the product should be kept in a dry environment. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	≤ 10.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.