Description

(S)-2-Amino-4-(Methylamino)-4-Oxobutanoic Acid is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its core value lies in its role as a key synthetic intermediate for constructing complex molecules with specific stereochemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and peptide mimetics. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in oncology and neurology research.
• Peptidomimetic Synthesis: Used to incorporate modified amino acid residues into peptide chains to enhance stability, bioavailability, or biological activity.
• Asymmetric Synthesis: Serves as a starting material or chiral auxiliary in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel chiral ligands for metal-catalyzed transformations.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-2-Amino-4-(Methylamino)-4-Oxobutanoic Acid
CAS No.	86070-35-1
Molecular Formula	C5H10N2O3
Molecular Weight	146.15 g/mol
Synonyms	(S)-2-Amino-N-methylsuccinamic Acid; (S)-2-Amino-4-(methylamino)-4-oxobutanoic Acid; L-2-Amino-4-(methylamino)-4-oxobutanoic Acid; (2S)-2-Amino-4-(methylamino)-4-oxobutanoic Acid; N-Methyl-L-asparagine; Nω-Methyl-L-asparagine; (S)-Asparagine, N-methyl-; L-N-Methylasparagine
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-4-(Methylamino)-4-Oxobutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications for research and pharmaceutical use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.