Description

Lhrh, n-Ac-Naphthyl(1)-(4-Cl-Phe)(2)-Trp(3)-Arg(6)-Ala(10)- CAS NO 86044-78-2 is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), featuring specific amino acid substitutions to modulate its biological activity and stability. This compound is of significant value for advanced research in endocrinology and the development of targeted therapeutic strategies. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on neuroendocrinology, oncology, and reproductive medicine.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) in the development of novel LHRH-based therapeutics.
• Endocrinology Studies: Used in vitro and in vivo to study the structure-activity relationship (SAR) of LHRH analogs and their interaction with gonadotropin-releasing hormone (GnRH) receptors.
• Oncology Research: Investigated for potential applications in hormone-dependent cancers, such as prostate and breast cancer, due to its ability to modulate hormonal pathways.
• Reproductive Biology: Employed in research models to understand and manipulate the hypothalamic-pituitary-gonadal axis.
• Biochemical Assay Development: Acts as a key component in the development and validation of high-throughput screening (HTS) assays and diagnostic kits.
• Peptide Chemistry & Conjugation: Provides a structurally modified peptide backbone for further chemical conjugation or labeling studies in drug delivery system development.

Basic Information

Item	Detail
Product Name	Lhrh, n-Ac-Naphthyl(1)-(4-Cl-Phe)(2)-Trp(3)-Arg(6)-Ala(10)- CAS NO 86044-78-2
CAS No.	86044-78-2
Molecular Formula	C64H83ClN16O12
Molecular Weight	1263.9 g/mol
Synonyms	LHRH Analog; [Ac-D-Nal(1), D-p-Cl-Phe(2), D-Trp(3), D-Arg(6), D-Ala(10)]-LHRH; GnRH Antagonist Analog; Cetrorelix Acetate Related Compound; (Ac-D-2-Nal1, D-4-Cl-Phe2, D-Trp3, D-Arg6, D-Ala10)-LHRH; Gonadorelin (5-L-tryptophan, 6-D-arginine, 10-D-alanine) analog; 86044-78-2; Luteinizing Hormone-Releasing Hormone Peptide Analog
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under strict quality management systems. Each batch undergoes comprehensive testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	5.0% - 12.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.