Description

4-Chloro-6-(4-Fluoro-Phenyl)-Pyrimidine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure makes it an essential intermediate for the development of active pharmaceutical ingredients (APIs) and agrochemicals, where precise chemical functionality is paramount. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides requiring specific halogenated pyrimidine cores.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and material science research.
• Active Pharmaceutical Ingredient (API) Manufacturing: An intermediate in multi-step synthesis processes for final API production under GMP guidelines.
• Ligand and Catalyst Development: Utilized in creating specialized ligands for catalytic systems and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Chloro-6-(4-Fluoro-Phenyl)-Pyrimidine
CAS No.	85979-61-9
Molecular Formula	C10H6ClFN2
Molecular Weight	208.62 g/mol
Synonyms	4-Chloro-6-(4-fluorophenyl)pyrimidine; 6-(4-Fluorophenyl)-4-chloropyrimidine; 4-Chloro-6-(p-fluorophenyl)pyrimidine; 4-Chloro-6-(4'-fluorophenyl)pyrimidine; Pyrimidine, 4-chloro-6-(4-fluorophenyl)-; 85979-61-9; 4-Chloro-6-(4-fluoro-phenyl)-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(4-Fluoro-Phenyl)-Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.