Description

2-Chloro-4-(4-Fluoro-Phenyl)-Pyrimidine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both chloro and fluoro substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the pyrimidine core into more complex structures.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploratory chemistry projects.

Basic Information

Product Name	2-Chloro-4-(4-Fluoro-Phenyl)-Pyrimidine
CAS No.	85979-59-5
Molecular Formula	C10H6ClFN2
Molecular Weight	208.62 g/mol
Synonyms	4-(4-Fluorophenyl)-2-chloropyrimidine; 2-Chloro-4-(4-fluorophenyl)pyrimidine; 2-Chloro-4-(p-fluorophenyl)pyrimidine; 85979-59-5; 4-(4-Fluorophenyl)-2-chloro-pyrimidine; Pyrimidine, 2-chloro-4-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(4-Fluoro-Phenyl)-Pyrimidine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.