Description

2-Chloro-4-(3-Fluoro-Phenyl)-Pyrimidine is a high-value halogenated pyrimidine building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in the development of advanced pharmaceutical agents and agrochemicals, enabling precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for custom synthesis projects requiring specific halogenated pyrimidine scaffolds.

Basic Information

Product Name	2-Chloro-4-(3-Fluoro-Phenyl)-Pyrimidine
CAS No.	85979-58-4
Molecular Formula	C10H6ClFN2
Molecular Weight	208.62 g/mol
Synonyms	2-Chloro-4-(3-fluorophenyl)pyrimidine; 4-(3-Fluorophenyl)-2-chloropyrimidine; 2-Chloro-4-(m-fluorophenyl)pyrimidine; 85979-58-4; Pyrimidine, 2-chloro-4-(3-fluorophenyl)-; 3-Fluoro-2-chloro-4-phenylpyrimidine (incorrect but common search variant)
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(3-Fluoro-Phenyl)-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.