Description

6-(4-Fluorophenyl)-4(1H)-Pyrimidinone is a high-purity fluorinated pyrimidinone derivative, a key heterocyclic building block in advanced organic synthesis. This compound is valued for its precise molecular structure, which is critical for developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the pyrimidinone core.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Material Science: Investigated for the development of organic electronic materials and advanced polymers.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process optimization projects.

Basic Information

Product Name	6-(4-Fluorophenyl)-4(1H)-Pyrimidinone
CAS No.	85979-57-3
Molecular Formula	C10H7FN2O
Molecular Weight	190.18 g/mol
Synonyms	4(1H)-Pyrimidinone, 6-(4-fluorophenyl)-; 6-(p-Fluorophenyl)-4-hydroxypyrimidine; 6-(4-Fluorophenyl)pyrimidin-4(1H)-one; 4-Hydroxy-6-(4-fluorophenyl)pyrimidine; 6-(4-Fluorophenyl)-4-pyrimidinol; 85979-57-3; 6-(4-Fluorophenyl)-1,4-dihydropyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 6-(4-Fluorophenyl)-4(1H)-Pyrimidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.