Description

4-(4-Fluorophenyl)Pyrimidin-2-Amine is a high-purity fluorinated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors, particularly in the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its fluorinated aromatic structure for enhanced bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated heterocyclic architectures.
• Academic & R&D: Used in university and institutional laboratories for fundamental research in organic chemistry and heterocyclic compound development.

Basic Information

Product Name	4-(4-Fluorophenyl)Pyrimidin-2-Amine
CAS No.	85979-49-3
Molecular Formula	C10H8FN3
Molecular Weight	189.19 g/mol
Synonyms	2-Amino-4-(4-fluorophenyl)pyrimidine; 4-(4-Fluorophenyl)-2-pyrimidinamine; 4-(p-Fluorophenyl)pyrimidin-2-amine; 2-Pyrimidinamine, 4-(4-fluorophenyl)-; 85979-49-3; 4-(4-Fluorophenyl)-2-aminopyrimidine; 4-(4-Fluorophenyl)-2-pyrimidinylamine
EINECS	Contact for details

Quality Control

Our 4-(4-Fluorophenyl)Pyrimidin-2-Amine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.