Description

Katacalcin is a bioactive peptide hormone derived from the calcitonin gene, playing a significant role in calcium homeostasis. Its primary value lies in its potent biological activity, making it a critical compound for advanced research and development in endocrinology and metabolic disorders. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on bone metabolism, calcium regulation, and related therapeutic areas. Katacalcin CAS NO 85916-47-8 is supplied as a high-purity material to ensure reliable and reproducible experimental results.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) in the development of novel therapeutics targeting bone diseases like osteoporosis and Paget's disease.
• Biochemical & Endocrine Studies: Used in vitro and in vivo to investigate its physiological role in calcium and phosphate metabolism, receptor binding studies, and signal transduction pathways.
• Diagnostic Kit Manufacturing: Serves as a critical calibrant or component in the production of immunoassay kits for measuring calcitonin gene-related peptides (CGRP) in clinical diagnostics.
• Academic & Preclinical Research: Fundamental tool for university and institutional labs studying comparative endocrinology, peptide hormone action, and metabolic regulation.
• Peptide Chemistry & Synthesis: Used as a benchmark compound for developing and optimizing peptide synthesis, purification, and analytical methods.

Basic Information

Product Name	Katacalcin
CAS No.	85916-47-8
Molecular Formula	C₁₃₈H₂₂₀N₄₀O₄₅
Molecular Weight	3084.5 g/mol
Synonyms	PDN-21; Calcitonin carboxyl-terminal peptide; Calcitonin gene-related peptide II (CGRP-II); Katacalcin (human); hPDN-21; Human PDN-21; Calcitonin precursor peptide; C-terminal flanking peptide of calcitonin
EINECS	Contact for details

Quality Control

Our Katacalcin is manufactured under strict quality management systems to ensure the highest standards of purity and consistency. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting research that demands reliable and reproducible performance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Assessed by functional assay (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.