Description

(-)-Quinpirole Hydrochloride is a potent and selective dopamine D2/D3 receptor agonist, widely recognized for its utility in neuroscience and pharmacological research. Its high purity and consistent quality are critical for generating reliable and reproducible data in receptor binding studies and behavioral experiments. This compound is essential for researchers and pharmaceutical developers in the fields of neuropharmacology, psychiatry, and central nervous system drug discovery.

Application

• Neuroscience Research: Used as a selective tool compound to study dopamine D2 and D3 receptor function, signaling pathways, and neurophysiology.
• Pharmacological Screening: Serves as a reference standard and agonist in high-throughput screening assays for identifying novel neuroactive compounds.
• Behavioral Studies: Applied in animal models to investigate the role of dopamine receptors in locomotion, reward, cognition, and addiction.
• Biochemical Assays: Utilized in in vitro receptor binding and functional assays (e.g., cAMP accumulation) to characterize drug-receptor interactions.
• Drug Discovery & Development: Acts as a key pharmacological agent in the preclinical development of therapeutics for Parkinson's disease, schizophrenia, and other CNS disorders.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies on the dopaminergic system.

Basic Information

Product Name	(-)-Quinpirole Hydrochloride
CAS No.	85798-08-9
Molecular Formula	C13H17N3O·HCl
Molecular Weight	267.76 g/mol
Synonyms	(-)-Quinpirole HCl; Quinpirole Hydrochloride; (4aR,8aR)-5-Propyl-1,4,4a,6,7,8,8a,9-octahydropyrazolo[3,4-g]quinoline Hydrochloride; LY-171555 Hydrochloride; trans-(-)-Quinpirole Hydrochloride; Quinpirole Monohydrochloride; Dopamine D2/D3 Receptor Agonist
EINECS	Contact for details

Quality Control

Our (-)-Quinpirole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.