Description

n-(2-((Trimethylsilyl)Oxy)Pyrimidin-4-Yl)Benzamide CAS NO 85743-99-3 is a specialized organosilicon-protected pyrimidine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a protected nucleoside or heterocyclic building block, enabling the precise construction of complex molecules under controlled conditions. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral, anticancer, or other biologically active pyrimidine-based compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that utilize modified pyrimidine scaffolds.
• Nucleoside Chemistry: Serves as a protected precursor for the synthesis of modified nucleosides and nucleotides, useful in medicinal chemistry and biochemistry.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for creating complex heterocyclic molecules in contract research and manufacturing.
• Material Science Research: Potential intermediate for creating organic semiconductors or ligands for metal-organic frameworks (MOFs) due to its functionalized aromatic system.

Basic Information

Product Name	n-(2-((Trimethylsilyl)Oxy)Pyrimidin-4-Yl)Benzamide
CAS No.	85743-99-3
Molecular Formula	C16H21N3O2Si
Molecular Weight	315.45 g/mol
Synonyms	Benzamide, N-[2-[(trimethylsilyl)oxy]-4-pyrimidinyl]-; 4-Pyrimidinamine, 2-[(trimethylsilyl)oxy]-N-phenyl-; N-(2-(Trimethylsilyloxy)pyrimidin-4-yl)benzamide; 2-(Trimethylsilyloxy)-N-phenyl-4-pyrimidinamine; 85743-99-3; TMS-protected 2-hydroxy-4-aminopyrimidine benzamide
EINECS	Contact for details

Quality Control

Our n-(2-((Trimethylsilyl)Oxy)Pyrimidin-4-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.