Description

2,4(1H,3H)-Pyrimidinedione, 5-Chloro-6-(Trifluoromethyl)- is a high-value halogenated pyrimidine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-purity building blocks for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside analogs and other potential therapeutic agents targeting viral and oncological diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated pyrimidine core for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of libraries of compounds for high-throughput screening in drug discovery.
• Material Science: Investigated as a monomer or additive for the synthesis of specialized polymers with unique electronic or thermal properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione, 5-Chloro-6-(Trifluoromethyl)-
CAS No.	85730-40-1
Molecular Formula	C5H2ClF3N2O2
Molecular Weight	214.53 g/mol
Synonyms	5-Chloro-6-(trifluoromethyl)uracil; 5-Chloro-6-(trifluoromethyl)-2,4-dihydroxypyrimidine; 5-Chloro-6-trifluoromethyluracil; 6-Trifluoromethyl-5-chlorouracil; 5-Chloro-6-trifluoromethyl-1H-pyrimidine-2,4-dione; 5-Chloro-6-(trifluoromethyl)-1H,3H-pyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-6-(trifluoromethyl)uracil adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and MS to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.