Description

4-Methoxy-2-Methylsulfanyl-6-(Trifluoromethyl)Pyrimidine is a high-value, multi-functional heterocyclic building block characterized by its trifluoromethyl and methoxy substituents. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its unique electronic properties and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and patentable novelty.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of antiviral, anticancer, and anti-inflammatory drug candidates, leveraging the trifluoromethyl group to improve lipophilicity and bioavailability.
• Agrochemical Active Ingredient Precursor: Used in the research and production of advanced herbicides, fungicides, and insecticides where the pyrimidine core provides specific biological targeting.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in the study of enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Methoxy-2-Methylsulfanyl-6-(Trifluoromethyl)Pyrimidine
CAS No.	85730-33-2
Molecular Formula	C7H7F3N2OS
Molecular Weight	224.21 g/mol
Synonyms	2-(Methylthio)-4-methoxy-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-4-methoxy-2-methylsulfanylpyrimidine; 4-Methoxy-2-(methylthio)-6-(trifluoromethyl)pyrimidine; 2-Methylsulfanyl-4-methoxy-6-trifluoromethylpyrimidine; 4-Methoxy-2-methylmercapto-6-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-Methylsulfanyl-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.