Description

Pirmagrel CAS NO 85691-74-3 is a selective and potent thromboxane A2 synthase inhibitor, a key compound in cardiovascular and antiplatelet research. Its primary value lies in its ability to modulate thromboxane A2 production, making it a critical tool for investigating platelet aggregation pathways and vascular tone. This product is essential for pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on developing novel therapeutics for thrombosis, atherosclerosis, and related cardiovascular disorders.

Application

• Pharmaceutical Reference Standard: Serves as a primary standard for analytical method development, validation, and quality control in drug substance and product manufacturing.
• Cardiovascular Research: A vital pharmacological tool for in vitro and in vivo studies targeting thromboxane-mediated platelet activation and vasoconstriction.
• Mechanistic Studies: Used to elucidate the role of thromboxane A2 in various disease models, including stroke, myocardial infarction, and inflammatory conditions.
• Drug Discovery & Development: Employed as a lead compound or benchmark in screening campaigns and structure-activity relationship (SAR) studies for new antiplatelet agents.
• Biochemical Assay Development: Utilized in enzymatic assays to study thromboxane synthase inhibition and its downstream biochemical effects.

Basic Information

Product Name	Pirmagrel
CAS No.	85691-74-3
Molecular Formula	C17H18N2O3
Molecular Weight	298.34 g/mol
Synonyms	Pirmagrel; 4-[(1-Imidazolyl)methyl]benzoic acid 2-(4-Morpholinyl)ethyl ester; U-63557A; 2-Morpholinoethyl 4-[(imidazol-1-yl)methyl]benzoate; 4-[(Imidazol-1-yl)methyl]benzoic Acid 2-Morpholinoethyl Ester; Benzoic acid, 4-[(1H-imidazol-1-yl)methyl]-, 2-(4-morpholinyl)ethyl ester; U 63557A
EINECS	Contact for details

Quality Control

Our Pirmagrel is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of residual solvents. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications. We support development projects requiring material that meets the stringent standards expected for pharmaceutical reference compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.