Description

4H-(1,2,4)Triazolo(4,3-A)(1,4)Benzodiazepine, 8-Chloro-6-(2-Chlorophen Yl)-1-((Ethylthio)Methyl)- CAS NO 85683-65-4 is a high-purity, complex heterocyclic compound belonging to the triazolobenzodiazepine class, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of specialized active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This product is essential for research institutions and pharmaceutical manufacturers focused on developing and producing innovative neuropharmacological agents and other specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel triazolobenzodiazepine-based Active Pharmaceutical Ingredients (APIs).
• Neuropharmacology Research: Used in preclinical and medicinal chemistry research for developing compounds targeting central nervous system (CNS) receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of specialized pharmaceuticals.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and development of proprietary drug candidates.

Basic Information

Product Name	4H-(1,2,4)Triazolo(4,3-A)(1,4)Benzodiazepine, 8-Chloro-6-(2-Chlorophen Yl)-1-((Ethylthio)Methyl)-
CAS No.	85683-65-4
Molecular Formula	C19H15Cl2N3S
Molecular Weight	388.31 g/mol
Synonyms	8-Chloro-6-(2-chlorophenyl)-1-((ethylthio)methyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine; 1-((Ethylthio)methyl)-8-chloro-6-(2-chlorophenyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine; Triazolobenzodiazepine Derivative; 85683-65-4; 8-Chloro-6-(2-chlorophenyl)-1-((ethylsulfanyl)methyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. Each batch is controlled via modern analytical techniques including HPLC, GC, and NMR to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.