Description

Furegrelate is a potent and selective thromboxane A2 synthase inhibitor, a key compound in biochemical and pharmacological research. Its primary value lies in its ability to modulate thromboxane A2 pathways, making it a critical tool for studying platelet aggregation, vasoconstriction, and related cardiovascular mechanisms. This high-purity compound is essential for researchers and developers in the pharmaceutical and life sciences industries, particularly those focused on cardiovascular disease research, anti-thrombotic drug discovery, and advanced biochemical assays.

Application

• Cardiovascular Research: A fundamental tool for investigating the role of thromboxane A2 in platelet activation, atherosclerosis, and vascular tone regulation.
• Anti-thrombotic Drug Development: Used as a reference standard and pharmacological probe in the discovery and validation of novel antiplatelet and anticoagulant agents.
• Biochemical Assays: Employed in in vitro enzymatic studies to specifically inhibit thromboxane synthase activity and measure downstream eicosanoid products.
• Pharmacology Studies: Utilized in animal models and tissue-based experiments to elucidate the pathophysiological effects of thromboxane A2 and evaluate therapeutic interventions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).

Basic Information

Product Name	Furegrelate
CAS No.	85666-24-6
Molecular Formula	C13H12F3NO3
Molecular Weight	287.24 g/mol
Synonyms	5-(3-Pyridinylmethyl)-2-benzofurancarboxylic acid, 1,1,1-trifluoro-2-methyl ester; Furegrelate sodium; U-63557A; Thromboxane A2 synthase inhibitor U63557; (±)-Furegrelate; 1,1,1-Trifluoro-2-methyl 5-[(3-pyridinyl)methyl]-2-benzofurancarboxylate
EINECS	Contact for details

Quality Control

Our Furegrelate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity determination by chromatographic techniques. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.