Description

4-Phenyl-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione is a specialized heterocyclic organic compound featuring a fused quinazoline-thione core structure. This compound serves as a valuable synthetic intermediate and building block in advanced organic chemistry and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, leveraging its complex heterocyclic scaffold.
• Material Science Precursor: Serves as a precursor for the synthesis of organic ligands or functional molecules used in catalysis or advanced materials.
• Academic & Contract Research: Essential for methodological studies in organic synthesis, heterocyclic chemistry, and the development of new synthetic routes.
• Chemical Biology Probe: Potential scaffold for developing tool compounds to study biological pathways and protein function.

Basic Information

Product Name	4-Phenyl-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione
CAS No.	85660-18-0
Molecular Formula	C20H16N2S
Molecular Weight	316.42 g/mol
Synonyms	4-Phenyl-1,2,3,4,5,6-hexahydrobenzo[h]quinazoline-2-thione; 2-Thioxo-4-phenyl-1,2,3,4,5,6-hexahydrobenzo[h]quinazoline; 4-Phenyl-3,4,5,6-tetrahydro-1H-benzo[h]quinazoline-2-thione; Benzo[h]quinazoline-2(1H)-thione, 3,4,5,6-tetrahydro-4-phenyl-; 85660-18-0
EINECS	Contact for details

Quality Control

Our 4-Phenyl-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.